Cleanliness is the first law of health

Sharp Drop in Gastrointestinal Infections During the COVID-19 Pandemic

The number of reported gastrointestinal infection outbreaks more than halved during the first six months of the COVID-19 pandemic in the UK, compared with the previous 5-year average, while lab-confirmed cases fell by a third.

Role of Hygiene Measures in Infection Reduction

While several factors are likely to have been behind these figures, the public health measures adopted to curb the spread of COVID-19 infection, such as improved hand hygiene, undoubtedly had a key role, say the researchers.

Long-Term Potential of Better Hygiene Practices

If this level of hygiene practice were to be maintained once the pandemic is over, there could be a permanent change in the number of gastrointestinal infections reported.

Broader Health Impacts of the Pandemic

While a growing body of evidence indicates that the pandemic and the mandatory infection control measures have had a significant impact on other health conditions, such as heart disease and cancer, it’s less clear what impact they’ve had on infectious diseases.

The Scale of Gastrointestinal Infections in the UK

In the UK alone, it is estimated that there are more than 17 million cases of gastrointestinal infections every year, resulting in over 1 million healthcare consultations and around 90,000 laboratory-confirmed diagnoses.

Study Objective: Analyzing Infection Control Measures

Researchers wanted to determine what impact the infection control measures imposed during the pandemic had on gastrointestinal infection trends in the first six months.

Specific Infection Control Measures Assessed

The infection control measures included:

• Improved hand hygiene

• Reduced social contact

• Social distancing

• Increased environmental cleaning

• Closure of premises

Data Sources and Surveillance Systems

The researchers drew on routinely collected health data from 7 English surveillance systems coordinated by the UK Health Security Agency (UKHSA), previously Public Health England, and Google Trend data, for the period 01 January to 2 August 2020 inclusive.

Types of Data Collected

The surveillance systems gather information on:

• Outbreaks

• Laboratory notifications

• Calls to the NHS 111 health advice service

• GP appointments

• Emergency care attendance

Pathogens of Interest

The study tracked microbes such as:

• Campylobacter spp

• Cryptosporidium spp

• Shiga-toxin producing E Coli (STEC)

• Giardia sp

• Listeria spp

• Norovirus

• Non-typhoidal Salmonella spp

• Shigella spp.

Timeline of Government Policy and Infection Trends

Data was divided into 7 pandemic response phases:

1. Pre-outbreak (phase 1).

2. Early outbreak (phase 2).

3. Pre-lockdown (phase 3).

4. Early lockdown (phase 4).

5. Late lockdown (phase 5).

6. Lockdown easing (phase 6)

7. Further easing (phase 7).

Researchers then compared this data with data collected from week 1 to week 31 in 2015–19 (5-year average).

Key Findings: Dramatic Declines in Outbreaks

During the first six months of 2020, 1544 suspected and lab-confirmed gastrointestinal infection outbreaks were reported in England, representing a 52% fall on the 5-year average for the period.

Decline by Phase

During the ‘pre-outbreak’ phase (weeks 1–4), notified outbreaks were comparable to previous years’ figures. But from week 7 (‘early outbreak’ phase), they were 22% lower than the previous 5-year average: 510 vs. 651. 

This trend continued until notified infection outbreaks were 87% lower by the ‘late lockdown’ phase (weeks 19–22): 46 vs. 350. And reported outbreaks remained substantially lower than historically observed for the duration of the response to the COVID-19 pandemic.

Virus-Related Outbreaks in Care Settings

Historically, most (95%) suspected or confirmed outbreaks of gastrointestinal infections reported in England are attributed to viruses and mostly occur in hospitals and care homes. 

Reductions by Pathogen Type

During phases 2–7 of the COVID-19 response, reported suspected and confirmed viral outbreaks fell by 62% (862 vs. 2239), with significant falls in parasitic infection outbreaks (2 vs. 32; 94% fall) and bacterial infection outbreaks (51 vs. 97 outbreaks; 47% fall). 

Lab-Confirmed Cases: A One-Third Decrease

Lab-confirmed infections also fell by a third (34%): 27,859 cases were reported between phases 2 and 7 compared with a 5-year average of 42,495. 

Seasonal Trends Persisted but at Lower Levels

While lab-confirmed infections began to increase from week 16 onwards, mirroring historic seasonal trends, they still remained below the 5-year average. 

During the historical peak for lab reporting, which occurred during lockdown easing, 4617 cases were reported; this compares with the 5-year average of 7879.

Age and Gender Disparities in Case Reductions

Reductions in lab-confirmed cases were observed for all pathogens across all age groups and in both sexes, ranging from:

• 26% in children aged 1–9 to

• 42% among women aged 80+

Why the Drop? Possible Explanations

According to the researchers, potential explanations for these trends include reductions in healthcare provision and unwillingness to seek medical attention. Emergency care attendances, GP consultations, and calls to the NHS 111 helpline for gastroenteritis and diarrhea/vomiting were all lower than in 2019. And while NHS 111 calls gradually increased, they remained substantially lower than in 2019. 

Evidence from Google Trends data showed searches for key phrases, such as ‘food poisoning,’ ‘gastroenteritis’ and ‘sickness bug’ all plunged between weeks 11 and 13, while trends for ‘handwashing’ and ‘disinfection’ rose substantially between weeks 8 and 14, mirroring patterns observed in other surveillance systems.

Limitations of the Study

This is an observational study and, as such, can’t establish causality. It only covered the first few months of the pandemic and couldn’t separate out the impact of other contributory factors, caution the researchers.

Conclusion: A Unique Opportunity to Sustain Lower Infection Rates

But they nevertheless conclude: “There has been a marked change in trends of [gastrointestinal] infections in the context of the COVID-19 pandemic. 

“The drivers of this change are likely to be multifactorial: while changes in health-seeking behavior, pressure on diagnostic services, and surveillance system ascertainment have undoubtedly played a role, there has likely been an actual decrease in the incidence for some pathogens resulting from the control measures and restrictions implemented. 

A Call for Continued Hygiene Habits

“This suggests that if some of these changes in behavior, such as improved hand hygiene, were maintained, then we could potentially see sustained reductions in the burden of [gastrointestinal] illness.”